Protein Modification Reagents
Medchemexpress LLC HY-103605 100mg Medchemexpress, (S,R,S)-AHPC-C6-PEG3-C4-Cl CAS:1835705-55-9 Purity:>98%
Medchemexpress, HY-103605 100mg (S,R,S)-AHPC-C6-PEG3-C4-Cl CAS:1835705-55-9 (S,R,S)-AHPC-C6-PEG3-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker. (S,R,S)-AHPC-C6-PEG3-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
ABclonal Technology PGC1α Rabbit pAb
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.
Medchemexpress LLC Azide-PEG-azide | 00-00-0 | 95.0% | 10MG
Azide-PEG-azide (MW 10000) is a bifunctional polyethylene glycol (PEG) linker with azide groups at both termini. It is designed for click chemistry conjugation and linker construction in chemical biology and medicinal chemistry, providing spacer length and solubility advantages for bioconjugation and PROTAC design.
- High average molecular weight suitable for spacing and solubility optimization.
- Azide termini enable copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- Good purity for research applications, supporting reproducible conjugation.
- Available in small-scale and bulk quantities for screening and scale-up.
- Stable under recommended storage, facilitating reliable long-term use.
Medchemexpress LLC Bromoacetamido-PEG5-azide | 1415800-37-1 | 95.5% | C14H27BrN4O6 | 10MG
Bromoacetamido-PEG5-azide is a heterobifunctional PEG-based linker used for PROTAC assembly and bioconjugation. It combines a bromoacetamido electrophile, which undergoes nucleophilic substitution with thiols and other nucleophiles, with an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC). The PEG5 spacer imparts flexibility and improved solubility, and the material is supplied at approximately 95.5% purity for research applications.
- Heterobifunctional design enables sequential orthogonal reactions.
- Bromoacetamido group reacts selectively with nucleophiles, such as thiols.
- Azide moiety compatible with CuAAC and SPAAC click chemistries.
- PEG5 spacer enhances solubility and conformational flexibility.
- Reported high purity suitable for research and synthesis workflows.
- Available in research-scale quantities for method development.
Medchemexpress LLC HY-103602A 100mg Medchemexpress, (S,R,S)-AHPC-PEG3-NH2 CAS:2010159-56-3 Purity:>98%
Medchemexpress, HY-103602A 100mg (S,R,S)-AHPC-PEG3-NH2 CAS:2010159-56-3 (S,R,S)-AHPC-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules DOTA-PEG5-C6-DBCO | Broadpharm |982.142 | C49H71N7O14 | 95.000 | OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCCOCCOCCNC(=O)CCCCC(=O)N2Cc3ccccc3C#Cc3ccccc23)CCN(CC(O)=O)CC1 | 1mg | 411413997
DOTA-PEG5-C6-DBCO | Broadpharm |982.142 | C49H71N7O14 | 95.000 | OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCCOCCOCCNC(=O)CCCCC(=O)N2Cc3ccccc3C#Cc3ccccc23)CCN(CC(O)=O)CC1 | 1mg | 411413997
Medchemexpress LLC Amino-PEG2-CH2CH2-SH (hydrochloride) | 3037676-58-4 | 95.0% | 201.71 g/mol | C6H16ClNO2S | 5 MG
Amino-PEG2-CH2CH2-SH (hydrochloride) is a PEG-based bifunctional linker for synthesis of PROTACs and conjugates. It features a primary amino group and a terminal thiol separated by a two-unit PEG spacer, supplied as the hydrochloride salt to aid stability and handling.
- Provides primary amino and terminal thiol functional groups for conjugation
- Two-unit PEG spacer offers flexibility and solubility
- Hydrochloride salt form improves stability and handling
- High purity suitable for synthetic applications
- Available in small milligram pack sizes for research use